COVID-19 Maternal and Infant Health Research Registries
Research is critical to tracking the impact of COVID-19 on maternal and infant health. By collecting clinical and survey data from pregnant women and babies during and following the COVID-19 pandemic, we can enhance and develop programs and policies that improve their care now and in the future.
Click on the links below to learn about the COVID-19 registries open to pregnant women and newborns who meet certain inclusion criteria.
Based in the United States:
- This nationwide study aims to will help patients and healthcare providers better understand how COVID-19 affects pregnant women and their newborns, including what their symptoms are, how long they last, and how COVID-19 may affect their pregnancy and/or delivery.
- Inclusion criteria: Pregnant women and postpartum women who have delivered within the past 6 weeks and who either have a confirmed COVID-19 diagnosis or are under observation for COVID-19.
- This registry is part of an observational research study that examines the short and long-term effect of COVID-19 in pregnancy and while breastfeeding. The research takes place via phone calls throughout pregnancy and post- delivery and may ask for breastmilk samples and medical records related to the pregnancy.
- Inclusion criteria: Currently pregnant, a resident of Canada or the U.S., and has known or suspected COVID-19 infection at any point in pregnancy or within 30 days of the last menstrual period before pregnancy.
- This registry from the University of Illinois at Chicago aims to understand how isolation, stress and changes in healthcare related to COVID-19 affect pregnancy and the postpartum period. Participation includes a 20- minute, anonymous survey and is open until July 3.
- Inclusion criteria: Women who are currently pregnant or have given birth since January 2020, at least 18 years old, able to read English and are in the United States
- This National Registry represents a collaboration between the American Academy of Pediatrics, Section on Neonatal-Perinatal Medicine (SONPM), the Vermont-Oxford Network (VON), and MedNAX (an organization of private neonatologists). This registry focuses on relative risks of transplacental, perinatal and postnatal transmission of COVID-19. It will provide population data on mother-infant dyads with the participation of hospitals around the US that have NICUs, by invitation. Once it reaches 25 mother/infant dyads, real-time descriptive data will be available weekly on the SONPM website.
- Inclusion criteria: Mother-infant dads, who deliver at a participating hospital, and test positive (the mom) for COVID-19 between 14 days before birth through 3 days after delivery.
Women’s Hospital of Baton Rouge, Louisiana:
- This study aims to gather data on how the COVID-19 pandemic is affecting pregnant women's health, feelings, behaviors and home/work situations. Participation includes weekly surveys and wellness check-ins. After birth, you may choose to link your responses to your baby's medical records.
- Inclusion criteria: Pregnant women who are at least 18 years old.
- This study is focused on vertical transmission of COVID-19 and includes collecting biological samples such as blood, cord blood, placenta, vaginal secretions or cervical mucous.
- Inclusion criteria: Women who are pregnant and have tested positive for COVID-19 at any point in pregnancy.
Registries outside the United States:
- This registry collects data to that will help better characterize the risks associated with COVID-19 infection during pregnancy for moms, fetuses and newborns through their physicians. This also will inform the creation of a responsive data system through a healthcare facilities network to ensure a rapid assessment of risks linked to future emergent pathogens.
- Inclusion criteria: Pregnant women, who are at least 18 years old, have consented to the registry and are believed to have COVID-19.
- This registry is a collaboration between Australian clinicians and international colleagues that aims to collect real-time data from pregnant women in Australia who are infected with COVID-19 to understand its impact on pregnancy outcomes. Hospital-based maternity units participate by expressing interest.
- Inclusion criteria: Please contact the organization for specifics.
- This study is using the UK Obstetric Surveillance System (UKOSS) to determine the incidence of hospitalization due to COVID-19 in pregnancy and assess the outcomes of the pandemic for mothers and infants. This study will also look at the effects of treatments.
- Inclusion criteria: Any woman admitted to a participating hospital in the UK with confirmed COVID-19 infection in pregnancy between the ages of 16-45. The surveillance period is March 1, 2020- March 31, 2021.
- This study is a collobaration between the National Perinatal Epidemiology Centre (NPEC), the National Women and Infants Health Programme (NWIHP) and the National Clinical Programme for Paediatrics and Neonatology (NCPPN). It is a retrospective medical chart review done to capture epidemiological and clinical characteristics of COVID-19 and outcomes.
- Inclusion criteria: Pregnant women and newborns before 29 days old who tested positive for COVID-19.
- This is a cohort study, coordinated by the University of Oxford, with the goal of assessing the effects of COVID-19 in pregnancy on maternal, fetal and neonatal outcomes worldwide. They are using an exposed and unexposed group to compare outcome differences and are monitoring their care until discharged from the hospital post-delivery. Primary outcomes will be categorized into a 'maternal morbidity index' and/or a 'severe neonatal morbidity index'.
- Inclusion criteria: Pregnant women with a laboratory confirmed COVID-19 or radiological pulmonary findings suggestive of COVID-19 or maternal symptoms compatible with COVID-19 or absense of symptoms but in close interaction with a confirmed case of COVID-19.
- This study is for pregnant women in the Netherlands who have a positive COVID-19 diagnosis. The surveillance system is looking at maternal and infant outcomes.
- Inclusion criteria: COVID-19 positive pregnant women in the Netherlands who have been identified via a contact person in each participating hospital or primary care midwives. Weekly registration takes place through NethOSS.
- Women can answer querstions related to COVID-19 during pregnancy to help other women who are pregnant or contemplating becoming pregnant and who are or may be infected with COVID-19.
- Inclusion criteria: Women over the age of 18 who are pregnant or have been pregnant in the last 6 months (even without a test) or tested for COVID-19 during pregnancy.
- This research will explore the experience of COVID-19 as well as miscarriage, fetal growth restriction and stillbirth, pre-term delivery and transmission from mother to baby. This international registry provides weekly data to health care communities and is available to the public online.
- Inclusion criteria: Pregnant women who are suspected to have COVID-19 or confirmed COVID-19 infection. Women will be recruited through their health care provider.