Request for Applications 2020 Research Program

AWARD DETAILS

March of Dimes leads the fight for the health of all moms and babies. For more than 80 years, March of Dimes has empowered families with programs, information and tools to have healthy pregnancies. Today we’re building on that legacy to level the playing field for all moms and babies, no matter their age, socio-economic background or demographics. We support moms throughout their pregnancy, even when things do not go according to plan. We advocate for policies that prioritize the health of moms and babies and pioneer research to find solutions to the biggest health threats they face. 

We invested in university-based March of Dimes Prematurity Research Centers, numerous Basil O’Connor awards and select individual research programs that specifically addressed premature birth.

UPDATE: The following grants have been awarded in 2020. Look back in early 2021 for information for the next funding cycle.  

March of Dimes 2020 grantees include the following research teams working on everything from the development of antibodies to prevent necrotizing enterocolitis, an aspirin regiment for preeclampsia and protocols addressing racial and health disparities in birth outcomes and so much more. 

  • Timothy Hand, MD, CHOP 
  • Drew Hall, MS, UCSD 
  • Dr. Rupsa Boelig, Thomas Jefferson University Hospitals 
  • Dr. Louise Laurent, UCSD 
  • Jennifer Condon, Ph.D., Wayne State University  
  • Elizabeth Howell, MD, Mount Sinai 
  • Dr. Miriam Kupperman, Ph.D, UCSF 
  • Deborah, Karasek, Ph.D., UCSF 
  • Michael  J. Morowitz, MD, UPMC Children’s Hospital of Pittsburgh 
  • Khosrow Adeli, Ph.D.,  The Hospital for Sick Children 
  • Dean Carson, Ph.D., Katana Pharmaceuticals 
  • Professor Ehud Gazit, Tel Aviv University 

 

RESEARCH GRANT PRIORITIES/AREAS OF INTEREST

  • Pregnancy-related disorders: Prevention and treatment of diseases in either mom, dad or baby that lead to premature birth, including studies addressing rising rates of infant and maternal mortality globally. This may include studies related to the period of preconception, gestation or the postpartum. Studies investigating environmental factors including stress and their effects on pregnancy and neonatal health are also welcome.  These studies addressing all these pregnancy-related disorders must have the potential to improve clinical care to prevent adverse maternal and child outcomes.
  • Genetic and environmentally-induced birth defects: Research leading to clinical impact in the areas of birth defect prevention and treatment. These studies must have the direct potential to improve the quality of life of those with birth defects and disabilities.
  • Opioid exposure and dependency: Research involving the behavioral, pharmacologic or mechanistic aspects of exposure to opioid and other harmful substances and resulting in interventions and therapies for moms and babies. These studies must have the potential to make a clinical impact in maternal and child health.
  • Health disparities surrounding all of the above areas: These studies must have the potential to make a clinical impact in maternal and child health.

RESEARCH GRANT CATEGORIES

Innovative Challenge Grants: Translational proposals in which a treatment/product/ intervention is the endpoint. The grant will be distributed in the following fashion: $50,000 for the first 6 months with clear cut deliverables defined in the application.  If these deliverables are achieved, the possibility of a second tranche in the amount of $100,000-500,000 will be awarded for 12 months, with the option of another 12 months of support if significant progress is made.  Each 12 month extension grant will have to be submitted as a new grant.  This mechanism will be similar to Phase I of a Small Business Innovation Research grant (NIH SBIR grant application) with the possibility of Phase II funding.

Novel Discovery Grants: Traditional research grants in translational or clinical science. These proposals should cover the translational spectrum from translation to humans, translation to patients, translation to practice and translation to population health. Animal model studies will not be funded unless they aim to validate something already established as a novel finding in humans or human tissues. The grant will be distributed in the following fashion: $50,000-100,000 for 12 months with the option of another 12 months of support if significant progress is made.  The 12 month extension grant will have to be submitted as a new grant.

Clinical and Social Science Challenge Grants: Clinical and social science proposals in the areas of maternal and child health. Topics requested include those exploring health equity in this area in order to reduce disparities, opioid dependency in mom, dad and baby to mitigate the rise in Neonatal Abstinence Syndrome, and premature birth and maternal/infant mortality. All studies must be novel and have the potential to significantly impact clinical care. The grant will be distributed in the following fashion: $50,000-100,000 for the first 6 months with clear cut deliverables defined in the application.  If these deliverables are achieved, the possibility of a second tranche in the amount of $100,000-500,000 will be awarded for 12 months, with the option of another 12 months of support if significant progress is made.  Each 12 month extension grant will have to be submitted as a new grant.

SUBMISSION PROCESS

The entire process must be completed online. Look back here in early 2021 for submission details.

Applicants may only submit one Letter of Intent to one of the Research Grant Categories.

REQUIRED INFORMATION FROM THE APPLICANT:

  • Letter of Intent for the proposed research (template provided), which includes the following information in this order:
    1. Title of proposal
    2. Hypothesis
    3. Preliminary data
    4. Statement of specific aims and methods of procedure
    5. Current financial support: list each current grant or contract for the conduct of this research. If there is no current support, state “NONE”
      Items 1-5 may not exceed 3 pages
  • Candidate’s biographical sketch
  • Facilities available 

QUESTIONS

Please direct any questions to [email protected].