Proteomics and other omics can be used to screen for various diseases throughout life. Proteins expressed at different levels can be markers for increased risk, or actual incidence of disease or condition. Our research into protein biomarkers aims to identify and characterize links between expression of these markers and adverse pregnancy outcomes.
Pregnancy is a complex and complicated process involving thousands of genes that are ‘turned on’ and ‘turned off’ in precise and specific sequences. How a sequence of events and the expression of the genes is timed is still largely unknown—however, the impacts of mistiming can be devastating. Our research into transcriptomics focuses on learning how signals and expression during normal and not-so-normal pregnancies compare and how those differences can signal to a care provider before clinical signs are present.
