Preeclampsia is a multi-system disorder of pregnancy characterized by abnormal placentation, vascular changes, and inflammation, often diagnosed based on new onset hypertension and proteinuria. Preventing and treating preeclampsia is a priority for maternal and child health. Low-dose aspirin (LDA) prescribed prenatally for patients at risk of preeclampsia is an underutilized preventive measure that can save lives, reduce morbidity, and lower healthcare costs. Despite recommendations, LDA remains underused in clinical practice, indicating an important quality improvement opportunity.
Low-Dose Aspirin for Preeclampsia Prevention: Implementation Guide for Clinical Teams was developed by California Maternal Quality Care Collaborative and March of Dimes. This implementation guide equips clinical teams with practical steps and evidence-based strategies to confidently offer low-dose aspirin to patients at risk for preeclampsia. It includes workflow tools, conversation guides, and patient education resources designed to support equitable care and improve maternal health outcomes.