The purpose of this article is to provide an overview of the risk factors, pathophysiology and management of preterm labor and premature birth. This article reviews known risk factors for spontaneous or indicated premature birth. Given the presence of certain risk factors, the ability to predict who will experience a premature birth can help nurses effectively provide care for mothers and their infants. Neither the authors nor any member of the planning committee for this activity has any financial, professional or personal relationships that could potentially bias the content. Fee will allow you to read and take CE test online 2.5 contact hours are available for this activity until 11/15/2018.