Retinopathy of prematurity (also called ROP) is an eye disease that affects many premature babies. A premature baby is one who is born too early, before 37 completed weeks of pregnancy. ROP happens when a baby’s retinas don’t fully develop in the weeks after birth. The retina is the nerve tissue that lines the back of the eye. ROP usually affects both eyes.
About 14,000 to 16,000 babies in the United States have ROP. Most babies with ROP have a mild case and don’t need treatment. But babies with severe ROP can have vision problems or blindness. About 400 to 600 babies each year become legally blind from ROP.
If your baby has ROP, getting treatment right away is really important. The disease can develop very quickly and take away your baby’s vision if it’s not checked carefully by his doctor at recommended checkups after he leaves the hospital. So, be sure to take your baby to all of his checkups and eye exams.
If your baby has ROP, visit our online community at shareyourstory.org to find a network of parents of babies with ROP. You can connect with them for support and comfort throughout your baby’s treatment.
During the last 12 weeks of pregnancy, a baby’s eyes develop quickly. When a baby’s born, most of the blood vessels in the retina are nearly grown. The retina usually finishes growing in the first few weeks after birth.
If a baby is born too early, his blood vessels may stop growing, or they may not grow correctly. These fragile vessels can leak, causing bleeding in the eye. Scar tissue can form, and if the scars shrink, they may pull the retina loose from the back of the eye. This is called retinal detachment. Retinal detachment is the main cause of vision problems and blindness in ROP.
Some things make a baby more likely than others to have ROP. These are called risk factors. Having a risk factor doesn’t mean for sure that your baby will have ROP. But it may increase his chances. We know that the smallest and sickest babies have more risk factors for ROP than larger, healthier babies. Risk factors for ROP include:
Your baby gets an eye exam for ROP if he:
For the eye exam, your baby sees a pediatric ophthalmologist. This is a doctor who identifies and treats eye problems in babies and children. Your baby gets her first eye exam 4 to 9 weeks after birth, depending on when she was born. She may still be in the newborn intensive care unit (also called NICU), or she may be home by this time. Babies born at 27 weeks or later usually have their first eye exam when they’re 4 weeks old. Babies born before 27 weeks usually have the exam later. This is because the more premature a baby is at birth, the longer it takes to develop serious ROP. This is why it’s so important to take your baby to all her eye exams, even after you take your baby home from the NICU.
If your baby’s first eye exam shows that the blood vessels in both retinas have finished normal development, she doesn’t need a follow-up exam. If your baby’s eye exam shows that she has ROP and her doctor thinks she needs treatment, she should start treatment within 72 hours. Early treatment gives your baby the best chance of having healthy vision.
Treatment depends on how severe your baby’s condition is. Any of the lower stages can get worse and become higher stages in just a few weeks. So it’s important to take your baby to all his checkups and eye exams so his doctor can make sure he’s getting any treatment he needs.
ROP treatment may include:
Many babies with ROP don’t need treatment. Even with treatment, some babies with ROP may have vision loss. And even if treatment works, babies with ROP are more likely than other babies to have some eye problems later in life, including:
This is why it’s so important to make sure your baby gets all his checkups and eye exams. Even though ROP goes away on its own for many babies, some babies do need treatment to get better. The more often your baby is checked for ROP and the sooner he’s treated, the less likely he is to have vision problems later in life. Even if your baby does not need treatment for ROP, she is more likely than other babies to have eye problems later in life. Ask your baby’s provider about eye exams at every checkup to help make sure ROP and other vision problems related to premature birth are diagnosed and treated as early as possible.
Last reviewed February 2013
Chronological age is the age of a baby from the day of birth. Adjusted age is the age of the baby based on his due date. To calculate adjusted age, take your baby's chronological age (for example, 20 weeks) and subtract the number of weeks premature the baby was (6 weeks). This baby's adjusted age (20 - 6) is 14 weeks. Health care providers may use this age when they evaluate the baby's growth and development. Most premature babies catch up to their peers developmentally in 2 to 3 years. After that, differences in size or development are most likely due to individual differences, rather than to premature birth. Some very small babies take longer to catch up.
Late preterm means that a baby is born after 34 weeks but before 37 weeks of pregnancy. It's important to try to have your baby as close to 39 weeks of pregnancy as possible. In the last few weeks of pregnancy, your baby's organs, like his brains, lungs and liver, are still growing. Waiting until you're at least 39 weeks also gives your baby time to gain more weight and makes him less likely to have vision and hearing problems after birth. Your baby will also be better able to suck and swallow and stay awake long enough to eat after he's born. Babies born early sometimes can't do these things.